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Secretariat – Math Department

Institute for Applied and Numerical Mathematics 2
Building 20.30 Room 3.012

Englerstraße 2
D-76131 Karlsruhe

Find us on the Campus Plan

Office hours:
Mon. - Thu.: 10:00-11:30

Tel.: +49 721 608 42680

E-mail: contact@lbrg.kit.edu

Secretariat – Process Engineering Department

Institute for Mechanical Process Engineering and Mechanics
Building 30.70 Room 205

Straße am Forum 8
D-76131 Karlsruhe

Find us on the Campus Plan

Office hours:
Mon. - Fri.: 9:00-12:00

Tel.: +49 721 608 42401

E-mail: contact@lbrg.kit.edu

Photo of Marie-Luise Maier Marie-Luise Maier

Office hour for students:
Room: 207 Institut für mechanische Verfahrenstechnik und Mechanik (30.70)
Tel.: +49 721 608 42429
Fax.: +49 721 608 42405
Email: marie-luise.maier@kit.edu

Institute for Mechanical Process Engineering and Mechanics
Karlsruhe Institute of Technology (KIT)
Building 30.70
Strasse am Forum 8
Germany - 76131 Karlsruhe

Multiphase flows are used in a variety of applications, such as protein (adsorptive) separation by high-gradient magnetic separation to specifically extract fermentation products from by-products. This method is based on adsorption processes in which the adsorptive binds to the functionalized surface of magnetic carrier particles. The separation step is carried out by magnetic forces, after that the elution takes place. In order to get a better insight into the whole process, the behaviour of the magnetic particles and the liquids (water, adsorptive) is investigated, mainly by simulation.

Bachelor or master thesis

Topics for a bachelor's or master's thesis can be chosen from the following areas:

  • Modeling and simulation of multiphase flows
  • Adsorption processes
  • Magnetic particle separation
  • Validation

For more information, please directly contact me. Additionally have a look here.

Research Interests

  • Multiphase flows (water, adsorptive, magnetic particles)
  • Magnetic particle separation by magnetic forces
  • Adsorption processes
  • Validation


M.-L. Maier, S. Milles, S. Schuhmann, G. Guthausen, H. Nirschl, M. J. Krause, Fluid
Flow Simulations Verified by Measurements to Investigate Adsorption Processes in a Static Mixer
, Computers & Mathematics with Applications, 2018.

M.-L. Maier, T. Henn, G. Thaeter, H. Nirschl, M. J. Krause, Multiscale Simulation with a Two-Way Coupled Lattice Boltzmann Method and Discrete Element Method, Chemical Engineering & Technology, 2017.


  1. M.-L. Maier, S. Janz, H. Nirschl, M.J. Krause, Lecture: Magnetic Particle Dynamics Combined with Protein Purification Modeled by Euler and Lagrange Approaches, 12th of September 2018, EFMC12 - 12 European Fluid Mechanics Conference, Vienna, Austria.
  2. M.-L. Maier, H. Nirschl, M.J. Krause, Lecture: Numerical Investigations of Magnetic Particle Agglomeration Combined with Adsorption Processes, 7th of March 2018, Jahrestreffen der ProcessNet-Fachgruppen Mehrphasenstroemungen, Bremen, Germany.
  3. M.-L. Maier, H. Nirschl, M.J. Krause, Lecture: Comparison of Physical and Numerical Experiments of Adsorption Processes in a Static Micro-Mixer, July 2017, ICMMES, Nantes, France.
  4. M.-L. Maier, H. Nirschl, M.J. Krause, Plenary lecture: Numerical Simulation of Adsorption Processes in a Static Micro-Mixer, 16th of March 2017, Jahrestreffen Dresden: Jahrestreffen der ProcessNet-Fachgruppen Mehrphasenstroemungen, Partikelmesstechnik, Zerkleinern und Klassieren, Computational Fluid Dynamics, Mischvorgaenge und dem TAK Aerosoltechnologie, Dresden, Germany.
  5. F. Klemens, M.-L. Maier, R. Trunk, Particulate Flows, 06th-10th of March 2017, Spring school talk: Lattice Boltzmann Methods with OpenLB Software Lab, Hammamet, Tunisia.
  6. M.-L. Maier, T. Henn, M.J. Krause, H. Nirschl, Lecture: Numerical Simulation of Magnetic Particle Separation: First Validation Results to LBM-DEM Coupling, 12th of April 2016, PARTEC 2016 – International Congress on Particle Technology, Nuernberg, Germany.
  7. M.-L. Maier, M.J. Krause, T. Henn, A. Mink, R. Trunk, H. Nirschl, W. Doerfler, Lecture: OpenLB, An Open Source Library for Parallel Lattice Boltzmann Fluid Flow Simulations, 7th – 10th of September 2015, 14th Workshop on Two-Phase Flow Predictions, Halle (Saale), Germany.

Recent Lectures and Courses